Journal: Poultry Science
Article Title: The chaperone DnaK promotes the emergence and accumulation of antibiotic-resistant clones through its ATPase activity in Riemerella anatipestifer
doi: 10.1016/j.psj.2025.105513
Figure Lengend Snippet: Telaprevir (TP) decreases the frequency of resistance in R. anatipestifer CH-1 . The frequency of resistance (FOR) for the WT was measured by plating the bacteria on the TSA containing different antibiotics and telaprevir. (A) The frequency of resistance (FOR) of the WT treated with or without TP to streptomycin (STR). (B) The frequency of resistance (FOR) of the WT treated with or without TP to gentamicin (GEN). (C) The frequency of resistance (FOR) of the WT treated with or without TP to ofloxacin (OFX). (D) The frequency of resistance (FOR) of the WT treated with or without TP to polymyxin B (PB). (E) The frequency of resistance (FOR) of the WT treated with or without TP to ampicillin (AMP). (F) The frequency of resistance (FOR) of the WT treated with or without TP to rifampin (RIF). Each point in the figure represents an independent experiment. The P values of the data were calculated by a t-test using GraphPad Prism 8. Asterisks denote significant differences (* P < 0.05, **** P < 0.0001, NM, not measured) between the 2 groups. Further, NM indicates not measured. Error bars represent SD ( n = 6).
Article Snippet: 10 9 cells were plated both on Tryptone Soya Agar (TSA) plates (OXOID, UK) with and without any antibiotics (STR, GEN, OFX, PB, AMP or RIF) (Meilunbio®, China).
Techniques: Bacteria